DIFFERENTIATION OF PATHOGENIC AND SAPROPHYTIC LEPTOSPIRES WITH 8-AZAGUANINE

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Differentiation of Pathogenic and Saprophytic Leptospires with 8-azaguanine.

Johnson, Russell C. (University of Minnesota, Minneapolis), and Palmer Rogers. Differentiation of pathogenic and saprophytic leptospires with 8-azaguanine. J. Bacteriol. 88:1618-1623. 1964.-The use of the purine analogue, 8-azaguanine, as a differential agent for the separation of pathogenic and saprophytic leptospires was investigated. Growth of strains of the saprophyte Leptospira biflexa was...

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In the process of studying conventional methods for differentiation of mycobacteria, a number of compounds were tested in this laboratory. Among them, hydroxylamine and 8-azaguanine were found to be useful. Among slowly growing mycobacteria, Mycobacterium tuberculosis and 11. bovis were distinguished from others by their sensitivity to both compounds; among rapidly growing mycobacteria, fortuit...

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Use of 8-azaguanine to differentiate leptospires isolated from Iowa surface waters.

Definitive classification of leptospires according to serotype rests with use of the microscopic agglutination and agglutinin-absorption tests. R. C. Johnson and P. Rogers (J. Bacteriol. 88:1618, 1964) observed inhibition of pathogenic serotypes by the purine analogue 8-azaguanine, whereas saprophytic serotypes were able to grow. This report is concerned with the effect of 8-azaguanine on growt...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1964

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.88.6.1618-1623.1964